Deskripsi

Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the selection of a particular machine and granulation method, is often done on the basis of tradition, rather than by using strict scientific or cost-benefit criteria. The basic techniques have changed dramatically in recent years and granulation for controlled release, extrusion, spheronisation, fluidization techniques, spray drying, melt extrusion, oral dispersion technology and roller compaction are new technologies that are increasingly being used in modern pharmaceutical production, which exhibit many advantages over previously available techniques. As with granulation, compression is also little understood and why some materials/formulations will compress well whilst others compact with difficulty, is slowly being elucidated. The Course will examine current granulation and compression theory and practice. Emphasis will be made as to how this theory and practice relates to current pharmaceutical development and production, with special reference to the machinery used. Scale-Up, Transfer Technology and SUPAC will also be addressed. A particular feature of the Course will be the workshop on new melt extrusion technology.

TUJUAN :

The aims of the Course are to provide a comprehensive and sound understanding of the theory and practice of tablet granulation and compression and to appreciate the various processes batch or continuous, that are available. The importance of the granulation process in producing good quality tablets will be emphasized. The modern techniques of extrusion, spheronisation, powder layering, roller compaction, fluid-bed processing, spray drying, melt extrusion, oral dispersion technology and tablet compression will be covered. The Course will be taught primarily by industrial scientists who have been closely involved with investigating these granulation and compression processes and thus a pragmatic approach will be adopted throughout.

Materi

Methods and Reasons for Granulating
Excipients
Properties of Granules
Granulation for Controlled Release
High Speed Granulation and End-Point Control
Integrated Mixer-Granulator Dryers
Fluid Bed Granulation
Layering
Spray Drying
Pellet Manufacture
Extrusion and Spheronization
Hot Melt Extrusion
Roller Compaction
Compression Theory
Compression Machinery
Compaction Simulators
Tabletting and Tooling Problems
Oral Dispersion Tabletting Technology
Scale-Up, Transfer Technology and Supac

Peserta

All who are working in pharmaceutical research, formulation, development, production, QA/QC and registration who require a sound understanding of the various granulation and compression methods and who wish to appreciate some of the advantages of the newer methods of granulation, spheronisation, roller compaction, layering, melt extrusion and compression that are now available.

Tempat

The Papandayan Hotel / The Jayakarta Suites, Boutique Hotel and spa

Instruktur

Ir. Chandra Wahyu Purnomo

Biaya

Biaya pelatihan sebesar Rp 7.500.000/peserta Non residensial. Khusus untuk pengiriman 3 peserta dari perusahaan yang sama, biaya pendaftaran sebesar Rp.7.000.000

Fasilitas

Meeting room at Hotel *****
Module / Handout
Training Kit
2x Coffee Break & Lunch
Flashdisk berisi materi
Exclusive Gifts
Certificate
Transportation during training

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